Patients should read and follow the product instructions carefully, including these steps for the safe storage, use and disposal of fentanyl patches to reduce the risk of accidental exposure: Storage: Keep patches in a safe place out of the reach of children, pets and others before use. Use: Patients or caregivers should check periodically that the patch is still in place, either by touching or looking at it, to make sure that it hasn’t fallen off. Patches that have become loose should be re-secured by taping the edges with first aid tape. Do not put your patch on in front of children, since they may copy your actions or think that the patch is a sticker or bandage. Disposal: Patients and caregivers should properly dispose of fentanyl patches immediately after use to prevent fatal accidents. Used patches must be folded so that the adhesive side sticks to itself, then returned to the pharmacy for disposal. They should never be placed in the household trash where children or pets can find them. Patients should dispose of unused patches remaining from a prescription as soon as they are no longer needed. Unused patches should be removed from their pouch and then appropriately discarded like used patches. If accidental exposure occurs: Remove the patch immediately and wash the area with lots of water. Do not use soap, alcohol, or other solvents as these may increase the drug’s ability to go through the skin. Get medical care right away. This is true for both fresh and used patches, as a considerable amount of drug remains in the patch after use – enough to cause serious harm. Signs of overdose: Signs of fentanyl overdose may include slow or weak breathing, dizziness, tiredness, extreme sleepiness, confusion, difficulty talking or walking, hallucination and seizures. The patch should be removed and emergency medical care contacted immediately.